Human CCR1 (NP 001286) VersaClone cDNA (10 UG)
货号：
RDC0001 基本售价：
2825.6 元 规格：
10 ug
产品信息
概述| 货号 | RDC0001 |
| 别名 | C-C chemokine receptor type 1; CC-CKR-1; CCR1; CCR-1; CD191 antigen; CD191; chemokine (C-C motif) receptor 1; CKR1; CKR-1; CMKBR1SCYAR1; CMKR1; HM145C-C CKR-1; LD78 receptor; Macrophage inflammatory protein 1-alpha receptor; MIP-1alpha-R; MIP1aR; RANTES receptor; RANTES-R |
| 反应种属 | Human |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 1230 (Human); 12768 (Mouse); 57301 (Rat) |
| 背景 | CCR1 is a G protein-coupled receptor member of the CC chemokine subfamily of receptors. Human CCR1 is 355 amino acids (aa) in length and has a predicted molecular weight of 41 kDa. Mouse and rat CCR1 share 80% aa sequence identity with the human protein. Most chemokine receptors exhibit promiscuous binding properties whereby several different chemokines signal through the same receptor. Chemokine ligand receptor binding results in G protein activation as well as the activation of downstream signaling cascades, including the Akt and NFkB pathways. Chemokine receptors mediate the chemotactic actions of chemokine ligands and activation of these receptors leads to cytoskeleton rearrangement and chemotactic cell migration. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 | - CC Chemokines and Receptors
- Chemokine Receptors
- Chemokines and Receptors in Allergy and Asthma
- Chemokines and Receptors in Angiogenesis
- Human CD Marker Products
- Monocyte Markers
- Multiple Myeloma
- Receptors in the Jak/STAT Pathway
- T Cell Migration/Adhesion
- Th1 Cells
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