概述| 货号 | RDC1414 |
| 别名 | B and T lymphocyte associated; B and T lymphocyte attenuator; B- and T-lymphocyte attenuator; B- and T-lymphocyte-associated protein; BTLA1; CD272 antigen; CD272; FLJ16065; MGC129743 |
全称 | B- And T-Lymphocyte Attenuator | | 反应种属 | Human |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 151888 (Human); 208154 (Mouse) |
| 背景 | BTLA (B- and T-lymphocyte attenuator; CD272) is a transmembrane immunoregulatory glycoprotein that is expressed on T cells, B cells, macrophages, dendritic cells, and NK cells. Its expression is low in naïve T cells and increases during antigen-specific induction of anergy. In B cells, BTLA expression is highest in mature naïve cells. BTLA binds to HVEM and negatively regulates homeostasis and inflammatory activation of CD8+ memory T cells and gamma/delta T cells. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 | - B Cell Activation
- Co-stimulatory and Co-inhibitory Molecules
- ITIM/ITAM Immunoreceptors and Related Molecules
- Leukocyte Receptors/Markers in Tfh Cell Differentiation and Function
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