概述| 货号 | RDC1229 |
| 别名 | GSF5; IGSF5; Immunoglobulin Superfamily 5 Like; Immunoglobulin Superfamily Member 5; Immunoglobulin Superfamily, Member 5; JAM4; JAM-4; JCAM; Junctional Adhesion Molecule 4; Putative Gene, Immunoglobulin Superfamily 5 Like11 |
全称 | Junctional Adhesion Molecule 4 | | 反应种属 | Human |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 150084 (Human); 72058 (Mouse) |
| 背景 | Members of the junctional adhesion molecule (JAM) family are type I transmembrane glycoproteins of the immunoglobulin (Ig) superfamily that are localized in the tight junctions between endothelial or epithelial cells and appear to be involved in leukocyte transmigration. JAM-A, also known as platelet adhesion molecule 1 (PAM-1) and platelet F11 receptor, contains two V-type Ig-like domains, forms homodimers, and interacts with LFA-1. JAM-B (vasculoendothelial or VE-JAM) and JAM-C each contain two Ig domains (one V-type and one C2-type), a cytoplasmic PDZ-binding motif and a PKC phosphorylation site. JAM-C interacts with MAC-1 and facilitates JAM-B interaction with integrin alpha 4 beta 1. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 | - Cell to Cell Adhesion Disassembly During EMT
- Epithelial Cell Polarity
- Immunoglobulin Superfamily CAMs
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