概述| 货号 | RDC0497 |
| 别名 | natural resistance-associated macrophage protein 1; LSH; member 1; NRAMP 1; NRAMP1solute carrier family 11 (sodium/phosphate symporters), member 1; NRAMPnatural resistance-associated macrophage protein 1; SLC11A1; solute carrier family 11 (proton-coupled divalent metal ion transporters) |
全称 | Natural Resistance-associated Macrophage Protein 1 | | 反应种属 | Human |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 6556 (Human); 18173 (Mouse); 316519 (Rat) |
| 背景 | SLC11A1 (NRAMP1) is a member of the solute carrier family of multi-pass membrane proteins. It functions as a proton-coupled divalent transition metal (iron and manganese) transporter involved in iron metabolism and host resistance to certain pathogens. Mutations in SLC11A1 have been associated with susceptibility to infectious diseases such as tuberculosis and leprosy, and inflammatory diseases such as rheumatoid arthritis and Crohn’s disease. Alternatively spliced variants that encode different protein isoforms have been described. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 | - Solute Carrier Family (SLC)
|
