概述货号 | RDC0177 |
别名 | MGC138426; parathyroid hormone 1 receptorMGC138452; parathyroid hormone/parathyroid hormone-related peptide receptor; parathyroid hormone/parathyroid hormone-related protein receptor; PFE; PTH/PTHr receptor; PTH/PTHrP type I receptor; PTH1 receptor; PTHR; PTHR1; PTHRPTHR1parathyroid hormone receptor 1; seven transmembrane helix receptor |
全称 | Parathyroid Hormone Receptor 1 | 反应种属 | Human |
性能供应商 | R&D Systems |
Entrez Gene IDs | 5745 (Human); 19228 (Mouse); 56813 (Rat) |
背景 | PTH1R (parathyroid receptor-1) is a 7-transmembrane receptor that expressed in bone, kidney and other tissues where its ligands, PTH (parathyroid hormone) and PTHrP (PTH-related protein), are found. Both gain and loss of function are associated with dwarfism in Jansen-type metaphyseal chondrodysplasia, or Blomstrand chondrodysplasia, respectively. Impaired function may be a factor in developmental endochondromas in Ollier disease. Polymorphisms may also be associated with variation in bone mineral density. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
参考文献 | - Cancer Biomarkers
- ICC / IHC Images: PTH1R/PTHR1
- Mini-review: Calcium & Phosphorus Metabolism
- Osteoblast and Osteoclast Markers
- Peptide Hormone G Protein-Coupled Receptors
- Protein/Peptide Hormones and Regulators
- Renal Markers
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