Human Fc epsilon RI beta/MS4A2 (NP 000130) VersaClone cDNA (10 UG)
货号：
RDC0229 基本售价：
2825.6 元 规格：
10 ug
产品信息
概述| 货号 | RDC0229 |
| 别名 | APY; ATOPY; Fc epsilon receptor I beta-chain; FCER1B; FCER1BIGEL; FCERI; High affinity immunoglobulin epsilon receptor beta-subunit (FcERI) (IgE Fcreceptor, beta-subunit) (Fc epsilon receptor I beta-chain); high affinity immunoglobulin epsilon receptor subunit beta; IgE Fc receptor subunit beta; IgE responsiveness (atopic); IGEL; IGER; IGHER; immunoglobulin E receptor, high affinity, beta polypeptide; Membrane-spanning 4-domains subfamily A member 2; membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, highaffinity I, receptor for; beta polypeptide); MS4A1; MS4A2 |
全称 | Fc epsilon Receptor I beta | | 反应种属 | Human |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 2206 (Human); 14126 (Mouse); 25316 (Rat) |
| 背景 | The allergic response involves the binding of allergen to receptor-bound IgE followed by cell activation and the release of mediators responsible for the manifestations of allergy. The IgE-receptor, a tetramer composed of an alpha, beta, and 2 disulfide-linked gamma chains, is found on the surface of mast cells and basophils. Fc epsilon RI beta/MS4A2 is the beta subunit of the high affinity IgE receptor which is a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. Fc epsilon RI beta seems to be a risk factor for atopic dermatitis and asthma. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 | - Dendritic Cell Pathogen Recognition/Uptake
- Fc Receptors
- Granulocyte Markers
- ITIM/ITAM Immunoreceptors and Related Molecules
- Leukocyte Receptors/Markers in Allergy and Asthma
- Monocyte Markers
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