概述| 货号 | RDC0645 |
| 别名 | 12-HETER; bA517H2.2 (G protein-coupled receptor 31); G protein-coupled receptor 31; HETER1; probable G-protein coupled receptor 31 |
全称 | G-Protein-Coupled Receptor 31 | | 反应种属 | Human |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 2853 (Human); 436440 (Mouse); 292310 (Rat) |
| 背景 | GPR31 is a plasma membrane G protein-coupled receptor (GPCR) that displays high affinity for 12-lipoxygenase-derived product 12-(S)-hydroxy-5,8,10,14-eicosatetraenoic acid (12-(S)-HETE). Knocking down GPR31 specifically inhibited 12-(S)-HETE-stimulated cell invasion. The diverse biological activities mediated by 12-(S)-HETE suggest that it functions as a critical signaling molecule in the regulation of physiological processes. 12-(S)-HETE/GPR31 binding leads to the activation of ERK1/2, MEK, and NF-kB. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 | - Bioactive Lipid G Protein-Coupled Receptors
- Cancer Biomarkers
- Eicosanoids and Regulators
- Steroid Hormones and Bioactive Lipids
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