概述| 货号 | RDC0522 |
| 别名 | HCRTR2; hypocretin (orexin) receptor 2; Hypocretin receptor type 2; Orexin Receptor 2; orexin receptor type 2; OX2R; Ox-2-R; ox2-R |
全称 | Hypocretin Receptor Type 2 | | 反应种属 | Human |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 3062 (Human); 387285 (Mouse); 25605 (Rat) |
| 背景 | Hypocretin receptor 2 (HCRTR2); also known as orexin receptor 2 or OX2R is a 40 kDa 7-transmembrane G-protein-coupled glycoprotein that is a high affinity receptor for orexins A and B (hypocretins 1 and 2). In mouse brain, engagement of HCRTRs promotes wakefulness, such that absence of either orexins or their receptors creates a narcolepsy-like state. HCRTR2 also influences reward circuits involving food or addictive drugs. The extracellular portions of human HCRTR2 share 92% and 93% aa identity with corresponding portions of mouse and rat HCRTR2, respectively. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 | - ICC / IHC Images: Orexin R2/HCRTR2
- Neurotransmitter G Protein-Coupled Receptors
- Peptide Hormone G Protein-Coupled Receptors
- Protein/Peptide Hormones and Regulators
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