Human Presenilin-2 (AAB59557) VersaClone cDNA (10 UG)
货号：
RDC1478 基本售价：
2825.6 元 规格：
10 ug
产品信息
概述| 货号 | RDC1478 |
| 别名 | AD3LP; AD4AD3L; AD5; E5-1; EC 3.4.23; EC 3.4.23.-; presenilin 2 (Alzheimer disease 4); presenilin-2; PS-2; PS2CMD1V; PSEN2; PSNL2; STM2STM-2 |
| 反应种属 | Human |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 5664 (Human) |
| 背景 | Presenilin-1 (PS-1) and Presenilin-2 (PS-2) are integral membrane proteins that contain multiple transmembrane domains. Both are predominantly located within the endoplasmic reticulum (ER) and early Golgi apparatus. They are primarily expressed in neurons and are ubiquitously expressed in the brain. PS-1 and PS-2 are proteolytically cleaved to generate an N-terminal fragment (NTF) and a C-terminal fragment (CTF). Mutations in the gene for Presenilin may play an important role in the pathology of Alzheimers disease. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 | - APP Cleavage and Amyloid-beta Degradation
- Aspartic Proteases and Regulators
- Mini-review: Alzheimers Disease
- Neurodegenerative Disease
- Notch Family
- Notch Pathway
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