Human CXCR2/IL-8 RB (AAB25880) VersaClone cDNA (10 UG)
货号：
RDC0027 基本售价：
2825.6 元 规格：
10 ug
产品信息
概述| 货号 | RDC0027 |
| 别名 | beta; CD182 antigen; CD182; CDw128b; chemokine (C-X-C motif) receptor 2; chemokine (CXC) receptor 2; C-X-C chemokine receptor type 2; CXCR2 gene for IL8 receptor type B; CXC-R2; CXCR-2; GRO/MGSA receptor; High affinity interleukin-8 receptor B; IL-8 receptor type 2; IL-8R B; IL8R2; IL8RA; IL8RB; interleukin 8 receptor B; interleukin 8 receptor type 2; interleukin-8 receptor type B |
全称 | Interleukin 8 Receptor B | | 反应种属 | Human |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 3579 (Human); 12765 (Mouse); 29385 (Rat) |
| 背景 | CXCR2/IL-8 RB is a member of the CXC chemokine receptor subfamily. Similar to other chemokine receptors, it is a G protein-coupled receptor (GPCR). Human CXCR2/IL-8 RB is 360 amino acids (aa) in length with a predicted molecular weight of 41 kDa. The human protein shares 71% aa sequence identity with the mouse and rat protein. CXCR2/IL-8 RB is expressed on neutrophils and activates neutrophil chemotaxis. Similar to the closely related CXCR1/IL-8 RA, CXCR2/IL-8 RB binds and mediates CXCL8/IL-8-induced neutrophil activation. It also binds additional CXC chemokine ligands that contain an ELR aa motif. CXCR2/IL-8 RB is implicated in neurological and pulmonary inflammatory diseases and injury. As such, it is a therapeutic target of interest in inflammatory disease and cancer. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 | - Chemokine Receptors
- Chemokines and Receptors in Angiogenesis
- Human CD Marker Products
- Macrophage Activation Markers
- Megakaryocytes
- Neuroinflammation
- Neutrophils
- T Cell Migration/Adhesion
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