概述| 货号 | RDC0305 |
| 别名 | G protein-coupled receptor 18; GPCRW; G-protein coupled receptor 18; NAGly Receptor; N-arachidonyl glycine receptor |
全称 | G Protein-coupled Receptor 18 | | 反应种属 | Human |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 2841 (Human); 110168 (Mouse); 679957 (Rat) |
| 背景 | GPR18, the most abundantly overexpressed orphan GPCR in all melanoma metastases, is constitutively active and inhibits apoptosis, indicating an important role for GPR18 in tumor cell survival. GPR18 is expressed significantly in lymphoid cell lines, but not in non-lymphoid hematopoietic cell lines. N-arachidonylglycine (NAGly) induces an increase in intracellular Ca(2+) concentration in GPR18-transfected cells. GPR18 may be considered a potential novel anticancer target in metastatic melanoma. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 | - Cancer Biomarkers
- Orphan G Protein-Coupled Receptors
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