概述| 货号 | RDC0739 |
| 别名 | ADHR; ADHRMGC138386; Antidiuretic hormone receptor; arginine vasopressin receptor 2; AVPR V2; AVPR2; DI1; DIR3; DIRNDI; NDI; Renal-type arginine vasopressin receptor; V2R; V2RMGC126533; vasopressin V2 receptor |
全称 | Arginine Vasopressin Receptor 2 | | 反应种属 | Rat |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 554 (Human); 12000 (Mouse); 25108 (Rat) |
| 背景 | AVPR2 is the vasopressin receptor, type 2, also known as the V2 receptor, which belongs to the seven-transmembrane-domain G protein-coupled receptor (GPCR) superfamily, and couples to Gs thus stimulating adenylate cyclase. The subfamily that includes AVPR2 is well conserved, though several members signal via other G proteins. AVPR2 is expressed in the kidney tubule, predominantly in the distal convoluted tubule and collecting ducts, where its primary property is to respond to the pituitary hormone arginine vasopressin (AVP) by stimulating mechanisms that concentrate the urine and maintain water homeostasis in the organism. When the function of this gene is lost, the disease Nephrogenic Diabetes Insipidus (NDI) results. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 | - Neurotransmitter G Protein-Coupled Receptors
- Peptide Hormone G Protein-Coupled Receptors
- Protein/Peptide Hormones and Regulators
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