| 货号 | 61759 |
| 别名 | Scm-Like With Four Mbt Domains 1, Renal Ubiquitous Protein 1, Smr, Sfmbt |
| 同种亚型 | IgG |
| 反应种属 | Mouse |
| 来源宿主 | Rabbit |
| 应用 | ChIP/Western Blot/Immunoprecipitation/Immunofluorescence |
| 使用方法 | Validated Applications: WB: 1:500 - 1:2,500 dilution Published Applications: ChIP IF IP WB See references for more information. Individual optimization may be required. |
| 供应商 | Active Motif |
| 纯化方式 | Affinity Purified |
| 免疫原 | This antibody was raised against a peptide within the C-terminal region of mouse SFMBT1. |
| 背景 | SFMBT1 (Scm-Like With Four Mbt Domains 1) is a histone-binding protein, which is part of various corepressor complexes. Mediates the recruitment of corepressor complexes to target genes, followed by chromatin compaction and repression of transcription. Plays a role during myogenesis: required for the maintenance of undifferentiated states of myogenic progenitor cells via interaction with MYOD1. Interaction with MYOD1 leads to the recruitment of associated corepressors and silencing of MYOD1 target genes. Part of the SLC complex in germ cells, where it may play a role during spermatogenesis. |
| 运输条件 | Blue Ice |
| 存放说明 | Antibodies in solution can be stored at -20°C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage. |
| 存储溶液 | Purified IgG in PBS with 30% glycerol and 0.035% sodium azide. Sodium azide is highly toxic. |
| 计算分子量 | 110 kDa |
| 参考文献 |
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SFMBT1 antibody (pAb) tested by Western blot. Detection of SFMBT1 antibody by Western blot. The analysis was performed using mouse testes nuclear extract (30 µg) and SFMBT1 antibody at a 1:1,000 dilution. |
