货号 | 61737 |
克隆类别 | 1H11-11 |
同种亚型 | IgG1 |
反应种属 | Human |
来源宿主 | Rat |
应用 | Western Blot |
使用方法 | Published Applications: WB See reference for more information. Individual optimization may be required. |
供应商 | Active Motif |
纯化方式 | Protein G Chromatography |
免疫原 | This antibody was raised against a peptide within the C-terminal region of human Histone H2A.Z.2.2. |
背景 | Histone H2A.Z (H2A Histone Family, Member V) is a histone H2A variant, a protein similar to canonical H2A but with different molecular identity and unique functions. H2A.Z is highly conserved during evolution. It plays an important role in basic cellular mechanisms such as gene activation, chromosome segregation, heterochromatic silencing and progression through the cell cycle. H2A.Z is acetylated at multiple lysine residues in its amino terminus, which may serve to allow H2A.Z to function as an insulator of chromatin domains. In the case of H2A.Z.2.2, this variant has been shown to be responsible for destabilization of the nucleosome through the chaperone complexes TIP60 and SRCAP. |
运输条件 | Blue Ice |
存放说明 | Antibodies in solution can be stored at -20°C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage. |
存储溶液 | Purified IgG in PBS with 30% glycerol and 0.035% sodium azide. Sodium azide is highly toxic. |
计算分子量 | 12 kDa |
参考文献 |
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