| 货号 | 61427 |
| 克隆类别 | 14G7-H9 |
| 同种亚型 | IgG2b |
| 反应种属 | Human |
| 来源宿主 | Mouse |
| 应用 | Western Blot/Immunofluorescence/Immunohistochemistry/Immunocytochemistry |
| 使用方法 | Validated Applications: WB: 1:300 - 1:1,000 dilution ICC/IF: 1:50 - 1:200 dilution Published Applications: ICC/IF IHC WB See references for more information. Individual optimization may be required. |
| 供应商 | Active Motif |
| 纯化方式 | Ascites |
| 免疫原 | Recombinant protein corresponding to amino acids 198-228 of human Histone macroH2A1.2. |
| 背景 | Histone macroH2A1.2 is a histone H2A variant and one of the three members of the macroH2A family. The three macroH2A proteins contain the C-terminal macro domain in addition to the H2A homologous region. This macro domain may bind poly ADP-ribose and other NAD+ metabolites. The macroH2A1.1 and macroH2A1.2 proteins are produced from alternatively spliced transcripts from the macroH2A1 gene while a second distinct macroH2A gene encodes macroH2A2. In mammals, macroH2A is preferentially localized to the inactive X chromosome and in general is proposed to play a role in repressing gene expression. In mice, macroH2A1 is required for the silencing of endogenous retroviruses. |
| 运输条件 | Blue Ice |
| 存放说明 | Some products may be shipped at room temperature. This will not affect their stability or performance. Upon receipt, unconjugated antibodies may be stored at -20°C for up to 2 years. Fluorophore- & enzyme-conjugated antibodies should be stored at 4°C. Fluorophore-conjugated antibodies should be protected from light. Keep reagents on ice when not in storage; to avoid repeated freeze/thaw cycles, we recommend aliquoting items that will be stored frozen into single-use fractions prior to freezing. |
| 存储溶液 | Ascites containing 30% glycerol and 0.035% sodium azide |
| 计算分子量 | 40 kDa |
| 参考文献 |
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