| 货号 | 61387 |
| 克隆类别 | 67-A2 |
| 同种亚型 | IgG1 |
| 反应种属 | Human, Mouse |
| 来源宿主 | Mouse |
| 应用 | Western Blot |
| 使用方法 | Validated Applications: WB: 0.5 - 2 µg/ml dilution |
| 供应商 | Active Motif |
| 纯化方式 | Protein A Chromatography |
| 免疫原 | This antibody was raised against a recombinant protein corresponding to amino acids 1028-1684 of human JMJD3 / KDM6B. |
| 背景 | JMJD3 / KMD6B (Jumonji domain-containing protein 3 lysine (K)-specific demethylase 6B) Histone demethylase that specifically demethylates Lys-27 of histone H3, thereby playing a central role in histone code. Demethylates trimethylated and dimethylated H3 Lys-27. Plays a central role in regulation of posterior development, by regulating HOX gene expression. Involved in inflammatory response by participating in macrophage differentiation in case of inflammation by regulating gene expression and macrophage differentiation. |
| 运输条件 | Blue Ice |
| 存放说明 | Antibodies in solution can be stored at -20°C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage. |
| 存储溶液 | Purified IgG in PBS with 30% glycerol and 0.035% sodium azide. |
| 计算分子量 | 150 kDa |
| 参考文献 |
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JMJD3/ KDM6B mAb (Clone 67-A2) tested by Western blot. JMJD3/ KDM6B detection by Western blot. The analysis was performed using cell lysate from BJ cells (lane 1) and BJ cells irradiated (lane 2). |
