货号 | 61161 |
克隆类别 | 8H6-2111 |
同种亚型 | IgG2a |
反应种属 | Human |
来源宿主 | Rat |
应用 | Western Blot/Immunofluorescence/Immunocytochemistry |
使用方法 | Published Applications: ICC/IF WB See references for more information. Individual optimization may be required. |
供应商 | Active Motif |
纯化方式 | Protein G Chromatography |
免疫原 | This H3.X/Y antibody was raised against a synthetic peptide corresponding to amino acids 9 - 20 of human H3.X. |
背景 | Histones H3.XandH3.Y are primate-specific variants of histone H3. H3.XandH3.Y are roughly 80% conserved compared to histone H3.3 The H3.Y protein is highly expressed in several primary cell lines, cancer cell lines and human brain. Expression of histone H3.Y is induced by stress. Exogenously expressed H3.X and H3.Y are efficiently incorporated into chromatin and exhibit dynamics similar to canonical histone H3. Knockdown of H3.Y results in slowed growth and altered expression of cell cycle related genes. |
运输条件 | Blue Ice |
存放说明 | Antibodies in solution can be stored at -80°C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage. |
存储溶液 | Purified rat IgG in PBS with 30% glycerol and 0.035% sodium azide. Sodium azide is highly toxic. |
计算分子量 | 17 kDa |
参考文献 |
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