| 货号 | 61341 |
| 克隆类别 | 1RC-1C10 |
| 别名 | Np95, hNP95, ICBP90, RNF106, hUHRF1, huNp95 |
| 同种亚型 | IgG1k |
| 反应种属 | Human |
| 来源宿主 | Mouse |
| 应用 | Western Blot/Immunoprecipitation/Immunofluorescence/Immunohistochemistry/Immunocytochemistry |
| 使用方法 | Validated Applications: ICC/IF: 0.5 µg/ml dilution Published Applications: IP ICC/IF IHC WB See references for more information. Individual optimization may be required. |
| 供应商 | Active Motif |
| 纯化方式 | Protein G Chromatography |
| 免疫原 | This antibody was raised against a synthetic peptide corresponding to amino acid residue(s) 263-793 of human Uhrf1. |
| 背景 | Uhrf1 (ubiquitin-like, containing PHD and RING finger domains 1) is a transcription and cell cycle regulator. It functions as a putative E3 ubiquitin-protein ligase. Uhrf1 is important for G1/S transition of the cell cycle. It is also believed that Uhrf1 may help recruit the DNA methyltransferase, DNMT1, to hemimethylated DNA and assist in the stabilization of DNMT1 with chromatin. |
| 运输条件 | Blue Ice |
| 存放说明 | Antibodies in solution can be stored at -20°C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage. |
| 存储溶液 | Purified IgG in 70 mM Tris (pH 8), 105 mM NaCl, 32 mM glycine, 0.07 mM EDTA, 30% glycerol, and 0.035% sodium azide. |
| 计算分子量 | 96 kDa |
| 参考文献 |
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Uhrf1 antibody (mAb) tested by Immunofluorescence. Formaldehyde fixed HeLa cells stained with Uhrf1 antibody at a 0.5 µg/ml dilution. |
