| 货号 | 61719 |
| 别名 | HCC5, P1.h, RLFB, P1-MCM3 |
| 同种亚型 | IgG |
| 反应种属 | Human |
| 来源宿主 | Rabbit |
| 应用 | Western Blot |
| 使用方法 | Validated Applications: WB: 1:500 - 1:2,000 dilution |
| 供应商 | Active Motif |
| 纯化方式 | Affinity Purified |
| 免疫原 | This antibody was raised against a full-length recombinant protein corresponding to human MCM3. |
| 背景 | MCM3 (Minichromosome Maintenance Complex Component 3) acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for once per cell cycle DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for DNA replication and cell proliferation. |
| 运输条件 | Blue Ice |
| 存放说明 | Antibodies in solution can be stored at -20°C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage. |
| 存储溶液 | Purified IgG in PBS with 50% glycerol and 0.02% sodium azide. Sodium azide is highly toxic. |
| 计算分子量 | 95 kDa |
| 参考文献 |
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MCM3 antibody (pAb) tested by Western blot. MCM3 detection by Western blot. The analysis was performed using HeLa nuclear cell extract (20 µg) and MCM3 antibody at a 1:1,000 dilution. |
