货号 | 61611 |
别名 | AN, AN2, FVH1, MGDA, WAGR, D11S812E |
同种亚型 | IgG |
反应种属 | Human |
来源宿主 | Rabbit |
应用 | Western Blot |
使用方法 | Validated Applications: WB: 1:500 - 1:1,000 dilution |
供应商 | Active Motif |
纯化方式 | Affinity Purified |
免疫原 | This antibody was raised against a peptide within the C-terminal region of human PAX6. |
背景 | PAX6 (Paired Box 6) is a transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. Required for the differentiation of pancreatic islet alpha cells (By similarity). Competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters. Regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains (By similarity). Isoform 5a appears to function as a molecular switch that specifies target genes. |
运输条件 | Blue Ice |
存放说明 | Antibodies in solution can be stored at -20°C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage. |
存储溶液 | Purified IgG in PBS with 30% glycerol and 0.035% sodium azide. Sodium azide is highly toxic. |
计算分子量 | 52 kDa |
参考文献 |
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PAX6 antibody (pAb) tested by Western blot. Detection of PAX6 by Western blot. The analysis was performed using 30 µg HEK293 nuclear extract and PAX6 (pAb) at a 1:500 dilution. |