货号 | 61591 |
别名 | WIP1, PP2C-DELTA |
同种亚型 | IgG |
反应种属 | Human |
来源宿主 | Rabbit |
应用 | Western Blot |
使用方法 | Validated Applications: WB: 1:250 - 1:500 dilution |
供应商 | Active Motif |
纯化方式 | Affinity Purified |
免疫原 | This antibody was raised against a peptide within the C-terminal region of human PPM1D. |
背景 | PPM1D (protein phosphatase 1D) is required for the relief of p53-dependent checkpoint mediated cell cycle arrest. Binds to and dephosphorylates Ser-15 of TP53 and Ser-345 of CHEK1 which contributes to the functional inactivation of these proteins. |
运输条件 | Blue Ice |
存放说明 | Antibodies in solution can be stored at -20°C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage. |
存储溶液 | Purified IgG in PBS with 30% glycerol and 0.035% sodium azide. Sodium azide is highly toxic. |
计算分子量 | 70 kDa |
参考文献 |
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PPM1D antibody (pAb) tested by Western blot. T-47D nuclear extract (40 µg) probed with PPM1D antibody at a dilution of 1:500. |