货号 | 61407 |
别名 | SET and MYND domain containing 3, KMT3E, ZMYND1, ZNFN3A1, bA74P14.1 |
同种亚型 | IgG |
反应种属 | Human |
来源宿主 | Rabbit |
应用 | Western Blot |
使用方法 | Validated Applications: WB: 1:500 - 1:1,000 dilution |
供应商 | Active Motif |
纯化方式 | Affinity Purified |
免疫原 | This antibody was raised against a peptide within human Smyd3. |
背景 | Smyd3 (SET and MYND domain containing 3) is a histone methyltransferase. Specifically methylates Lys-4 of histone H3, inducing di- and tri-methylation, but not monomethylation. Plays an important role in transcriptional activation as a member of an RNA polymerase complex. Binds DNA containing 5-CCCTCC-3 or 5-GAGGGG-3 sequences. Recently, Smyd3 was described as the methyltransferase responsible for a novel site of histone modification, H4K5 methylation, |
运输条件 | Blue Ice |
存放说明 | Antibodies in solution can be stored at -20°C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage. |
存储溶液 | Purified IgG in PBS with 30% glycerol and 0.035% sodium azide. |
计算分子量 | 50 kDa |
参考文献 |
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Smyd3 antibody (pAb) tested by Western blot. K-562 nuclear extract (30 µg) probed with Smyd3 antibody at a dilution of 1:500. |