| 货号 | 61267 |
| 别名 | CSX, CSX1, VSD3, CHNG5, HLHS2, NKX2E, NKX2-5, NKX4-1 |
| 同种亚型 | IgG |
| 反应种属 | Human |
| 来源宿主 | Rabbit |
| 应用 | Western Blot |
| 使用方法 | Validated Applications: WB: 1:500 - 1:1,000 dilution |
| 供应商 | Active Motif |
| 纯化方式 | Affinity Purified |
| 免疫原 | This NKX2.5 antibody was raised against a peptide within the N-terminal region of human NKX2.5. |
| 背景 | TheNKX2.5 (NK2 homeobox 5, CSX, Homeobox protein CSX, NKX2E, Homeobox protein NK-2 homolog E, NK2 transcription factor related, locus 5, CHNG5, cardiac-specific homeobox 1) gene encodes a homeobox-containing transcription factor that functions in heart formation and development. Alternative splicing results in multiple transcript variants. Implicated in commitment to and/or differentiation of the myocardial lineage. Acts as a transcriptional activator of ANF in cooperation with GATA4. Also interacts with JARID2 which represses its ability to activate transcription of ANF. |
| 运输条件 | Blue Ice |
| 存放说明 | Antibodies in solution can be stored at -20°C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage. |
| 存储溶液 | Purified IgG in PBS with 30% glycerol and 0.035% sodium azide. Sodium azide is highly toxic. |
| 计算分子量 | 35 kDa |
| 参考文献 |
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NKX2.5 antibody (pAb) tested by Western blot Nuclear extract of human heart cells (20 µg) probed with NKX2.5 antibody (1:1,000). |
