| 货号 | 61263 |
| 别名 | Proline, Glutamate And Leucine Rich Protein 1, HMX3, MNAR, P160 |
| 同种亚型 | IgG |
| 反应种属 | Human |
| 来源宿主 | Rabbit |
| 应用 | Western Blot |
| 使用方法 | Validated Applications: WB: 1:500 dilution The addition of 0.05% Tween 20 in the blocking buffer and primary antibody incubation buffer is recommended to aid in detection by Western blot. Individual optimization may be required. |
| 供应商 | Active Motif |
| 纯化方式 | Affinity Purified |
| 免疫原 | This PELP1 antibody was raised against a peptide within the internal region of human PELP1. |
| 背景 | ThePELP1 gene (proline, glutamic acid and leucine rich protein 1, Modulator of non-genomic activity of estrogen receptor, HMX3, MNAR, P160) encodes a protein that is a coactivator of estrogen receptor-mediated transcription and a corepressor of other nuclear hormone receptors and sequence-specific transcription factors. Plays a role in estrogen receptor (ER) genomic activity when present in the nuclear compartment by activating the ER target genes in a hormonal stimulation dependent manner. PELP1 interacts with KDM1 (LSD1) and may act as reader of histone methyl modifications for ER mediated gene activation. |
| 运输条件 | Blue Ice |
| 存放说明 | Antibodies in solution can be stored at -20°C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage. |
| 存储溶液 | Purified IgG in PBS with 30% glycerol and 0.035% sodium azide. Sodium azide is highly toxic. |
| 计算分子量 | 150 kDa |
| 参考文献 |
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PELP1 antibody (pAb) tested by Western blot Whole cell extract of MCF-7 cells (30 µg) probed with PELP1 antibody (1:500). |
