货号 | 61249 |
别名 | LDS3, LDS1C, MADH3, JV15-2, HSPC193, HsT17436 |
同种亚型 | IgG |
反应种属 | Human |
来源宿主 | Rabbit |
应用 | Western Blot |
使用方法 | Validated Applications: WB: 1:500 - 1:1,000 dilution The addition of 0.05% Tween 20 in the blocking buffer and primary antibody incubation buffer is recommended to aid in detection by Western blot. Individual optimization may be required. |
供应商 | Active Motif |
纯化方式 | Affinity Purified |
免疫原 | This SMAD3 antibody was raised against a peptide within human SMAD3 (mothers against decapentaplegic homolog 3). |
背景 | ThisSMAD3 (mothers against decapentaplegic homolog 3, mad3, MAD homolog 3) protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene mothers against decapentaplegic (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor-beta and is thought to play a role in the regulation of carcinogenesis. |
运输条件 | Blue Ice |
存放说明 | Antibodies in solution can be stored at -20°C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage. |
存储溶液 | Purified IgG in PBS with 30% glycerol and 0.035% sodium azide. Sodium azide is highly toxic. |
计算分子量 | 52kD |
参考文献 |
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SMAD3 antibody (pAb) tested by Western blot. Whole cell extract of A549 cells (30 µg) probed with SMAD3 antibody (1:500). |