货号 | 61237 |
别名 | PC3, RC1 |
同种亚型 | IgG |
反应种属 | Human |
来源宿主 | Rabbit |
应用 | Western Blot |
使用方法 | Validated Applications: WB: 1:500 dilution |
供应商 | Active Motif |
纯化方式 | Affinity Purified |
免疫原 | This CBX8 antibody was raised against a peptide corresponding to the C-terminal region of human CBX8 (Chromobox protein homolog 8). |
背景 | CBX8 (chromobox homolog 8, PC3, RC1) is a Component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A Lys-119, rendering chromatin heritably changed in its expressibility. |
运输条件 | Blue Ice |
存放说明 | Antibodies in solution can be stored at -20°C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage. |
存储溶液 | Purified IgG in PBS with 30% glycerol and 0.035% sodium azide. Sodium azide is highly toxic. |
计算分子量 | 45kD |
参考文献 |
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CBX8 antibody (pAb) tested by Western blot. Whole-cell extract of HeLa cells (20 µg) probed with CBX8 antibody (1:500). |