| 货号 | 61189 |
| 别名 | TCF, HNF4, MODY, MODY1, NR2A1, TCF14, HNF4a7, HNF4a8, HNF4a9, NR2A21, HNF4alpha |
| 同种亚型 | IgG |
| 反应种属 | Human |
| 来源宿主 | Rabbit |
| 应用 | Western Blot/Immunofluorescence/Immunocytochemistry |
| 使用方法 | Validated Applications: ICC/IF: 1:2,000 dilution WB: 1:500 - 1:2,000 dilution For optimal results, primary antibody incubations should be performed at 4°C. Individual optimization may be required. |
| 供应商 | Active Motif |
| 纯化方式 | Affinity Purified |
| 免疫原 | This HNF4A antibody was raised against a peptide derived from the N-terminal region of human HNF4A. |
| 背景 | HNF4A (hepatocyte nuclear receptor 4A, NR2A1, TCF14) is an orphan nuclear receptor and activator of transcription. HNF4A is major regulator of the hepatocytic phenotype and regulates genes involved in the control of lipid homeostasis. Mutations in HNF4A can cause maturity onset diabetes of the young (MODY1). HNF4A binds DNA as a homodimer and is involved in the development of the liver, kidney and intestine. |
| 运输条件 | Blue Ice |
| 存放说明 | Antibodies in solution can be stored at -20°C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage. |
| 存储溶液 | Purified IgG in PBS with 30% glycerol and 0.035% sodium azide. Sodium azide is highly toxic. |
| 计算分子量 | 60 kDa |
| 参考文献 |
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HNF4A antibody (pAb) tested by Immunofluorescence. Formaldehyde fixed HeLa cells stained with HNF4A antibody at a 1:2,000 dilution. | |
HNF4A antibody (pAb) tested by Western blot. Whole cell extract (20 µg) of Hep G2 cells probed with HNF4A antibody at a dilution of 1:500. |
