| 货号 | 61117 |
| 别名 | EGRA, TIEG, EGR-alpha |
| 同种亚型 | IgG |
| 反应种属 | Human |
| 来源宿主 | Rabbit |
| 应用 | Western Blot |
| 使用方法 | Validated Applications: WB: 1:500 - 1:1,000 dilution |
| 供应商 | Active Motif |
| 纯化方式 | Affinity Purified |
| 免疫原 | This TIEG1 / KLF10 antibody was raised against a peptide derived from human TIEG1 / KLF10. |
| 背景 | TIEG1/KLF10 (Transforming growth factor β-inducible early gene 1, Kruppel-like factor 10) is a transcriptional regulator involved in the control of cell growth. KLF10 binds to Sp1 / GC rich DNA sequences and can activate or repress the transcription of a number of genes. KLF10 is especially important for osteoblast function, including bone mineralization and support of osteoclast differentiation. KLF10 is rapidly induced by TGFβ, bone morphogenetic protein, estrogen and epidermal growth factor. KLF10 plays a major role in TGFβ-mediated inhibition of cell proliferation and inflammation and induction of apoptosis. |
| 运输条件 | Blue Ice |
| 存放说明 | Antibodies in solution can be stored at -20°C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage. |
| 存储溶液 | Purified IgG in 70 mM Tris (pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30% glycerol and 0.035% sodium azide. Sodium azide is highly toxic. |
| 计算分子量 | 50 kDa |
| 参考文献 |
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Western Blot: K-562 nuclear extract (20 µg per lane) probed with the TIEG1 / KLF10 antibody (pAb) at a dilution of 1:500. |
