| 货号 | 61041-AM |
| 别名 | BABL, LIPO, HMGIC, STQTL9 |
| 同种亚型 | IgG |
| 反应种属 | Human |
| 来源宿主 | Rabbit |
| 应用 | Western Blot/Immunoprecipitation |
| 使用方法 | Validated Applications: IP: 10 µl per IP WB: 1:1,000 - 1:5,000 dilution |
| 供应商 | Active Motif |
| 纯化方式 | Affinity Purified |
| 免疫原 | This HMGA2 antibody was raised against a peptide within the N-terminal region of human HMGA2 / HMGI-C. |
| 背景 | HMGA2(High-mobility group AT-hook protein 2, HMGI-C) is a member of the HMG (High mobility group) protein family, which are non-histone chromatin-associated proteins involved in DNA organization and regulation of transcription. The HMG protein family consists of six proteins and is subdivided into three subfamilies: the HMG-1/-2 subfamily, the HMG-I/Y subfamily and the HMG-14/-17 subfamily. Mouse models of HMGA2 function indicate that it is involved in proliferation at the cellular level and obesity at the organismal level. Overexpression of HMGA2 is observed in a variety of cancers. |
| 运输条件 | Blue Ice |
| 存放说明 | Antibodies in solution can be stored at -20°C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage. |
| 存储溶液 | Purified IgG in 70 mM Tris (pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30% glycerol and 0.035% sodium azide. Sodium azide is highly toxic. |
| 计算分子量 | 20 kDa |
| 参考文献 |
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HMGA2 / HMGI-C antibody (pAb) tested by Immunoprecipitation. 10 µl of HMGA2 / HMGI-C antibody was used to immunoprecipitate HMGA2 / HMGI-C from 250 µg of HepG2 nuclear cell extract (lane 2). 10 µl of rabbit IgG was used as a negative control (lane 1). The immunoprecipitated protein was detected by Western blotting using the HMGA2 / HMGI-C antibody at a dilution of 1:3,000. | |
HMGA2 / HMGI-C antibody (pAb) tested by Western blot. Detection of HMGA2 / HMGI-C by Western blot. Nuclear extract (25 µg) of mouse ES cells probed with HMGI-C / HMGA2 antibody at a dilution of 1:3,000. |
