货号 | 40914 |
别名 | MYD88D |
同种亚型 | IgG |
反应种属 | Human |
来源宿主 | Rabbit |
应用 | Western Blot |
使用方法 | Validated Applications: WB: 2 - 4 µg/ml dilution For optimal results, primary antibody incubations should be performed at room temperature. The addition of 0.1% Tween 20 to all Blotto solutions may also reduce background. Individual optimization may be required. |
供应商 | Active Motif |
纯化方式 | Affinity Purified |
免疫原 | This MyD88 antibody was raised against a synthetic peptide corresponding to amino acid residues 233-248 of human MyD88. |
背景 | MyD88 is an adapter protein involved in the Toll-like receptorandIL-1 receptor signaling pathway in the innate immune response. MyD88 acts via IRAK1, IRAK2 and TRAF6, leading to NFκB activation, cytokine secretion and the inflammatory response. MyD88 increases IL-8 transcription, and may be involved in myeloid differentiation. |
运输条件 | Blue Ice |
存放说明 | Antibodies in solution can be stored at -80°C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage. |
存储溶液 | PBS containing 0.02% sodium azide. Sodium azide is highly toxic. |
计算分子量 | 35 kDa |
参考文献 |
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MyD88 pAb tested by Western blot. MyD88 detection by Western blot. The analysis was performed using Jurkat whole-cell extract and MyD88 pAb at a 2 µg/ml dilution. |