| 货号 | 39867 |
| 别名 | KAT6A, MYST3, ZNF220, RUNXBP2, ZC2HC6A |
| 同种亚型 | IgG |
| 反应种属 | Human |
| 来源宿主 | Rabbit |
| 应用 | Western Blot |
| 使用方法 | Validated Applications: WB: 1:200 - 1:500 dilution The addition of 0.05% Tween 20 in the blocking buffer and primary antibody incubation buffer is recommended to aid in detection by Western blot. Individual optimization may be required. |
| 供应商 | Active Motif |
| 纯化方式 | Affinity Purified |
| 免疫原 | This MOZ antibody was raised against a synthetic eptide within the N-terminal half of human MOZ (Monocytic leukemia zinc finger protein aka histone acetyltransferase MYST3). |
| 背景 | MOZ(Monocytic leukemia zinc finger protein) / MYST3 (also known KAT6A) is a histone acetyltransferase specific for H3. It is part of the MOZ/MORF protein complex and is involved in the activation of transcription. Specifically, it is known to interact with and serve as a co-activator for RUNX1 and RUNX2. MOZ/MYST3 is found concentrated in sub-nuclear foci that are distinct from PML bodies. Chromosomal aberrations involving MYST3 may be a cause of acute myeloid leukemias. MYST3-NCoA2 has been shown to bind CBP and disrupt its transcriptional activation function. |
| 运输条件 | Blue Ice |
| 存放说明 | Antibodies in solution can be stored at -20°C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage. |
| 存储溶液 | Purified IgG in 70 mM Tris (pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30% glycerol and 0.035% sodium azide. Sodium azide is highly toxic. |
| 计算分子量 | 290 kDa |
| 参考文献 |
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MOZ antibody (pAb) tested by Western blot. Nuclear extract of K-562 cells (40 μg) probed with MOZ antibody at a dilution of 1:500. |
