货号 | 39825 |
别名 | HOX1, ABD-B, HOX1G, HOX1.7 |
同种亚型 | IgG |
反应种属 | Human |
来源宿主 | Rabbit |
应用 | Western Blot |
使用方法 | Validated Applications: WB: 1:500 - 1:2,000 dilution The addition of 0.05% Tween 20 in the blocking buffer and primary antibody incubation buffer is recommended to aid in detection by Western blot. Individual optimization may be required. |
供应商 | Active Motif |
纯化方式 | Affinity Purified |
免疫原 | This HOXA9 antibody was raised against a peptide within the N-terminal region of human HOXA9. |
背景 | HOXA9 (Homeobox protein A9, HOX1G) is a sequence-specific DNA binding transcription factor with a central role in both hematopoiesis and leukemia. HOXA9 is required for normal hematopoiesis and contributes to myeloid blood cell differentiation. High levels of HOXA9 expression in hematopoietic cells is a characteristic feature of acute myeloid leukemia (AML), and may contribute to the development of this disease. Overexpression of HOXA9 markedly expands hematopoietic stem cells. |
运输条件 | Blue Ice |
存放说明 | Antibodies in solution can be stored at -20°C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage. |
存储溶液 | Purified IgG in 70 mM Tris (pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30% glycerol and 0.035% sodium azide. Sodium azide is highly toxic. |
计算分子量 | 48 kDa |
参考文献 |
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HOXA9 antibody (pAb) tested by Western blot. K-562 nuclear extract (20 µg per lane) probed with HOXA9 antibody at a dilution of 1:1,000. |