| 货号 | 39302 |
| 别名 | CCD, CCD1, CLCD, OSF2, CBFA1, OSF-2, PEA2aA, PEBP2aA, CBF-alpha-1 |
| 同种亚型 | Serum |
| 反应种属 | Human |
| 来源宿主 | Rabbit |
| 应用 | Electrophoretic Mobility Shift Assay |
| 使用方法 | Validated Applications: EMSA: 2 - 6 µl per assay Published Applications: see references The addition of Tris-glycine electrophoresis buffer for supershift assays is recommended. |
| 供应商 | Active Motif |
| 纯化方式 | None |
| 免疫原 | This AML-3/Runx2 antibody was raised against a synthetic peptide corresponding to amino acid residues 333-348 of human AML-3/Runx2. |
| 背景 | AML-3(acute myeloid leukemia 3 protein) also known as Runx2(runt-related transcription factor 2) is a multifunctional transcription factor that can either activate or repress transcription. The alpha subunit can bind DNA as a monomer, or DNA binding can be increased by heterodimerization. AML-3 is necessary for osteoblastic differentiation and skeletal morphogenesis. |
| 运输条件 | Blue Ice |
| 存放说明 | Antibodies in solution can be stored at -80°C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage. |
| 存储溶液 | PBS containing 0.2% gelatin, 0.01% thimersol and 0.1% sodium azide. Thimersol and sodium azide are highly toxic. |
| 计算分子量 | 56 kDa |
| 参考文献 |
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AML-3/Runx2 pAb tested by supershift. Detection of AML-3/Runx2 by EMSA analysis. AML-3/Runx2 pAb was used in a supershift assay (EMSA) with Saos-2 nuclear extract (lane 4). |
