| 货号 | 39301 |
| 别名 | CBFA3, PEBP2aC |
| 同种亚型 | Serum |
| 反应种属 | Human |
| 来源宿主 | Rabbit |
| 应用 | Electrophoretic Mobility Shift Assay |
| 使用方法 | Validated Applications: EMSA: 4 - 6 µl per assay Published Applications: see references The addition of Tris-glycine electrophoresis buffer for supershift assays is recommended. |
| 供应商 | Active Motif |
| 纯化方式 | None |
| 免疫原 | This AML-2 antibody was raised against a full-length protein corresponding to human AML-2/Runx3. |
| 背景 | AML-2(acute myeloid leukemia 2 protein) also known as Runx3(Runt-related transcription factor 3) is a member of the DNA binding alpha subunit of the heterodimeric transcription factor complex PEBP2/CBF. AML-2 can either activate or repress transcription, and it also interacts with other transcription factors. AML-2 expression is regulated by AML-1/Runx1. |
| 运输条件 | Blue Ice |
| 存放说明 | Antibodies in solution can be stored at -80°C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage. |
| 存储溶液 | PBS containing 0.2% gelatin, 0.01% thimersol and 0.1% sodium azide. Thimersol and sodium azide are highly toxic. |
| 计算分子量 | 44 kDa |
| 参考文献 |
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AML-2/Runx3 antibody tested by supershift. Detection of AML-2/Runx3 by EMSA analysis. AML-2/Runx3 antibody was used in a supershift assay (EMSA) with Raji nuclear extract (lane 4). |
