| 货号 | 39095 |
| 别名 | LMNB1, LMN, ADLD, LMN2, LMNB |
| 同种亚型 | Serum |
| 反应种属 | Human, Mouse |
| 来源宿主 | Rabbit |
| 应用 | Western Blot |
| 使用方法 | Validated Applications: WB: 1:100 - 1:500 dilution Published Applications: see references For optimal results, primary antibody incubations should be performed at room temperature. The addition of 0.1% Tween 20 to all Blotto solutions may also reduce background. Individual optimization may be required. |
| 供应商 | Active Motif |
| 纯化方式 | None |
| 免疫原 | This Lamin B1 antibody was raised against a full-length protein corresponding to human Lamin B1. |
| 背景 | Lamin B1(LMN,ADLD), along with the A and C Lamins are involved in maintaining the spatial organization of nuclear compartments. Depletion of Lamin B1 results in the disruption of RNA synthesis by RNA pol II, and eventually migration of chromatin to the nuclear periphery and dispersion of the nucleoli. The role of Lamin B1 in maintaining the nucleoskeleton may be to bind to nucleophosmin/B23. |
| 运输条件 | Blue Ice |
| 存放说明 | Antibodies in solution can be stored at -80°C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage. |
| 存储溶液 | Rabbit serum containing 0.1% sodium azide. Sodium azide is highly toxic. |
| 计算分子量 | 66-70 kDa |
| 参考文献 |
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Lamin B1 antibody tested by Western blot. Lamin B1 detection by Western blot analysis. Lamin B1 is detected in HeLa nuclear extracts using Lamin B1 rabbit polyclonal antibody at a 1:100 (lane 1) and a 1:500 (lane 2) dilution. |
