货号 | 39213 |
别名 | ANP32A, LANP, MAPM, PP32, HPPCn, PHAP1, PHAPI, I1PP2A, C15orf1 |
同种亚型 | IgG |
反应种属 | Human |
来源宿主 | Rabbit |
应用 | Western Blot |
使用方法 | Validated Applications: WB: 1:500 - 1:1,000 dilution For optimal results, primary antibody incubations should be performed at room temperature. The addition of 0.1% Tween 20 to all Blotto solutions may also reduce background. Individual optimization may be required. |
供应商 | Active Motif |
纯化方式 | Affinity Purified |
免疫原 | This INHAT-2/pp32 antibody was raised against a mixture of synthetic peptides corresponding to amino acid residues 87-103 and 231-246 of human INHAT-2/pp32. |
背景 | INHAT(pp32) binds to histones and masks them from being substrates for histone acetyltransferases (HATs). Endogenous INHAT subunits, which include the Set/TAF-I beta oncoprotein, and pp32 associate with chromatin in vivo and can block coactivator mediated transcription when transfected in cells. Single phosphorylations within the Histone H3 tail blocks binding of INHAT, as well as simultaneous acetylation of multiple lysine residues. |
运输条件 | Blue Ice |
存放说明 | Some products may be shipped at room temperature. This will not affect their stability or performance. Upon receipt, unconjugated antibodies may be stored at -20°C for up to 2 years. Fluorophore- & enzyme-conjugated antibodies should be stored at 4°C. Fluorophore-conjugated antibodies should be protected from light. Keep reagents on ice when not in storage; to avoid repeated freeze/thaw cycles, we recommend aliquoting items that will be stored frozen into single-use fractions prior to freezing. |
存储溶液 | PBS containing 0.02% sodium azide and 0.1 mg/ml BSA. Sodium azide is highly toxic. |
计算分子量 | 31 kDa |
参考文献 |
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