| 货号 | 39202 |
| 别名 | TAF1A, SL1, RAFI48, TAFI48 |
| 同种亚型 | IgG |
| 反应种属 | Human, Mouse, Rat |
| 来源宿主 | Rabbit |
| 应用 | Western Blot |
| 使用方法 | Validated Applications: WB: 1 - 2 µg/ml dilution Published Applications: see references For optimal results, primary antibody incubations should be performed at room temperature. The addition of 0.1% Tween 20 to all Blotto solutions may also reduce background. Individual optimization may be required. |
| 供应商 | Active Motif |
| 纯化方式 | Affinity Purified |
| 免疫原 | This INHAT-1/TAF-1a/TAF-1b antibody was raised against a mixture of synthetic peptides corresponding to amino acid residues 66-81 and 135-151 of human INHAT-1/TAF-1a/TAF-1β. |
| 背景 | INHAT (also designated TAF-1α, TAF-1β and inhibitor of histone acetyltransferases complex) binds to histones and masks them from being substrates for histone acetyltransferases (HATs). Endogenous INHAT subunits, which include the Set/TAF-Ibeta oncoprotein, and pp32 associate with chromatin in vivo and can block coactivator-mediated transcription when transfected in cells. Single phosphorylations within the Histone H3 tail blocks binding of INHAT, as well as simultaneous acetylation of multiple lysine residues. |
| 运输条件 | Blue Ice |
| 存放说明 | Antibodies in solution can be stored at -80°C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage. |
| 存储溶液 | PBS containing 0.02% sodium azide and 0.1 mg/ml BSA. Sodium azide is highly toxic. |
| 计算分子量 | 37 kDa |
| 参考文献 |
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INHAT-1/TAF-1α/TAF-1β pAb tested by Western blot. INHAT-1 detection by Western blot. The analysis was performed using Jurkat whole-cell extract and INHAT-1/TAF-1α/TAF-1β pAb at a 2 µg/ml dilution. |
