货号 | 39201 |
别名 | APEX2, XTH2, ZGRF2 |
同种亚型 | IgG |
反应种属 | Human |
来源宿主 | Rabbit |
应用 | Western Blot |
使用方法 | Validated Applications: WB: 1:500 - 1:1,000 dilution For optimal results, primary antibody incubations should be performed at room temperature. The addition of 0.1% Tween 20 to all Blotto solutions may also reduce background. Individual optimization may be required. |
供应商 | Active Motif |
纯化方式 | Affinity Purified |
免疫原 | This APEXL2 antibody was raised against a synthetic peptide corresponding to human APEXL2. |
背景 | APEXL2(APEX2, apurinic endonuclease-like 2 or apyrimidinic endonuclease-like 2) is a multifunctional DNA repair enzyme. The main role of APE is to create a nick in the phosphodiester backbone of the AP site that is created when DNA glycosylase removes the damaged base. Four types of APE (AP endonucleases) are classified according to their site of incision. APEXL2(APEX2) is a Class II AP endonuclease that cleaves the phosphodiester backbone 5′ to the AP site; it may also be present in the mitochondria. |
运输条件 | Blue Ice |
存放说明 | Some products may be shipped at room temperature. This will not affect their stability or performance. Upon receipt, unconjugated antibodies may be stored at -20°C for up to 2 years. Fluorophore- & enzyme-conjugated antibodies should be stored at 4°C. Fluorophore-conjugated antibodies should be protected from light. Keep reagents on ice when not in storage; to avoid repeated freeze/thaw cycles, we recommend aliquoting items that will be stored frozen into single-use fractions prior to freezing. |
存储溶液 | PBS containing 0.02% sodium azide. Sodium azide is highly toxic. |
计算分子量 | 54 kDa |
参考文献 |
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