货号 | 61473 |
克隆类别 | SN4-1 |
别名 | Staphylococcal Nuclease And Tudor Domain Containing 1, p100, TDRD11 |
同种亚型 | IgG1 |
反应种属 | Human, Mouse |
来源宿主 | Mouse |
应用 | Western Blot/Immunoprecipitation/Immunofluorescence/Immunohistochemistry/Immunocytochemistry |
使用方法 | Published Applications: IP ICC/IF IHC WB See references for more information. Individual optimization may be required. |
供应商 | Active Motif |
纯化方式 | Protein A Chromatography |
免疫原 | This antibody was raised against a recombinant protein corresponding to amino acids 505 - 674 of human SND1. |
背景 | SND1 (staphylococcal nuclease and tudor domain containing 1) functions as a transcriptional coactivator and a modulator of RNA metabolism. As a transcriptional coactivator, it acts as a bridging factor between STAT6 and the basal transcription factors, plays a role in PIM1 regulation of MYB activity and is a transcriptional coactivator for the Epstein-Barr virus nuclear antigen 2 (EBNA2). SND-1 has been identified as part of the RISC complex (RNA-induced silencing complex) and interacts with Ago-2. It is involved in the degradation of hyper-edited inosine containing microRNA precursors as part of the RNA interference pathway. |
运输条件 | Blue Ice |
存放说明 | Antibodies in solution can be stored at -20°C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage. |
存储溶液 | Purified IgG in PBS with 30% glycerol and 0.035% sodium azide. Sodium azide is highly toxic. |
计算分子量 | 115 kDa |
参考文献 |
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