货号 | 61345 |
克隆类别 | 1YO-1B10 |
别名 | Splicing Factor 3b Subunit 3, RSE1, SAP130, SF3b130, STAF130 |
同种亚型 | IgG1k |
反应种属 | Human, Mouse |
来源宿主 | Mouse |
应用 | Western Blot/Immunoprecipitation |
使用方法 | Published Applications: IP WB See references for more information. Individual optimization may be required. |
供应商 | Active Motif |
纯化方式 | Protein G Chromatography |
免疫原 | This antibody was raised against a peptide corresponding to amino acid residue(s) 1057-1076 of human Sf3b3. |
背景 | Sf3b3 (splicing factor 3b, subunit 3, 130kDa) is a subunit of the splicing factor SF3B required for A complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the E complex. Belongs also to the minor U12-dependent spliceosome, which is involved in the splicing of rare class of nuclear pre-mRNA intron. |
运输条件 | Blue Ice |
存放说明 | Antibodies in solution can be stored at -20°C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage. |
存储溶液 | Purified IgG in 70 mM Tris (pH 8), 105 mM NaCl, 32 mM glycine, 0.07 mM EDTA, 30% glycerol, and 0.035% sodium azide. |
计算分子量 | 135 kDa |
参考文献 |
本官网所有报价均为常温或者蓝冰运输价格,如有产品需要干冰运输,需另外加收干冰运输费。 |