| 货号 | 61339 |
| 克隆类别 | 2ATX-2B1 |
| 别名 | Ataxin 7 Like 3, SAGA-Associated Factor 11 Homolog |
| 同种亚型 | IgG1k |
| 反应种属 | Human, Mouse |
| 来源宿主 | Mouse |
| 应用 | Western Blot/Immunoprecipitation |
| 使用方法 | Published Applications: IP WB See references for more information. Individual optimization may be required. |
| 供应商 | Active Motif |
| 纯化方式 | Protein G Chromatography |
| 免疫原 | This antibody was raised against a synthetic peptide corresponding to amino acid residue(s) 278-296 of human Atxn7l3. |
| 背景 | Atxn7l3 (ataxin 7-like 3) is a component of the transcription regulatory histone acetylation (HAT) complex SAGA (Spt-Ada-Gcn5-Acetyltransferase), a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and ENY2 into the SAGA complex. |
| 运输条件 | Blue Ice |
| 存放说明 | Antibodies in solution can be stored at -20°C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage. |
| 存储溶液 | Purified IgG in 70 mM Tris (pH 8), 105 mM NaCl, 32 mM glycine, 0.07 mM EDTA, 30% glycerol, and 0.035% sodium azide. |
| 计算分子量 | 40 kDa |
| 参考文献 |
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