| 货号 | 61159 |
| 克隆类别 | CHU61 |
| 别名 | Pim-2 Proto-Oncogene, Serine/Threonine Kinase |
| 同种亚型 | IgG2a |
| 反应种属 | Human |
| 来源宿主 | Rat |
| 应用 | Western Blot/Immunohistochemistry |
| 使用方法 | Validated Applications: IHC: 2 µg/ml dilution WB: 0.5 - 2 µg/ml dilution For optimal results, IHC should be performed on paraffin sections. Frozen sections are not recommended. |
| 供应商 | Active Motif |
| 纯化方式 | Protein G Chromatography |
| 免疫原 | This PIM2 antibody was raised against a recombinant protein corresponding to human PIM2. |
| 背景 | PIM2 is a serine/threonine protein kinase in the CAMK family. PIM2 promotes cell survival in response to a variety of proliferative signals through activation of the I-κB kinase/NF-κB pathway. It also inhibits apoptosis through the phosphorylation of BAD. PIM2 has been implicated in the transformation of both T and B lymphocytes and is highly expressed in human leukemia and lymphomas, as well as adenocarcinomas and hepatocellular carcinomas. |
| 运输条件 | Blue Ice |
| 存放说明 | Antibodies in solution can be stored at -80°C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage. |
| 存储溶液 | Purified rat IgG in PBS with 30% glycerol and 0.035% sodium azide. Sodium azide is highly toxic. |
| 计算分子量 | 37 kDa |
| 参考文献 |
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Immunohistochemistry using PIM2 mAb. PIM2 detected by immunohistochemistry in paraffin-embedded human tonsil cells. | |
Western blot of PIM2 antibody (mAb). Ramos cell extract (100 µg per lane) probed with PIM2 antibody (mAb). |
