货号 | 61075 |
克隆类别 | 6A10 |
别名 | MRTL, MYCC, c-Myc, bHLHe39 |
同种亚型 | IgG2a |
反应种属 | Human |
来源宿主 | Rat |
应用 | Western Blot/Immunoprecipitation/Electrophoretic Mobility Shift Assay |
使用方法 | Published Applications: IP EMSA WB See references for more information. Individual optimization may be required. |
供应商 | Active Motif |
纯化方式 | Protein G Chromatography |
免疫原 | This c-Myc antibody was raised against a recombinant protein corresponding to amino acids 1-262 of human c-Myc protein. |
背景 | c-Myc (Myc) is a sequence specific DNA binding transcription factor that regulates gene expression, especially genes involved in cell division. Myc family members contain a basic Helix-Loop-Helix leucine zipper (bHLHZ) domain. Myc family proteins associated with thousands of genes, especially those involved in cell growth and proliferation. c-Myc serves as an integrator of signal transduction, linking extracellular signals to an acute cellular growth response. Mutations and overexpression of c-Myc are associated with cell proliferation and cancer. |
运输条件 | Blue Ice |
存放说明 | Antibodies in solution can be stored at -20°C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage. |
存储溶液 | Purified IgG in 70 mM Tris (pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30% glycerol and 0.035% sodium azide. Sodium azide is highly toxic. |
计算分子量 | 68 kDa |
参考文献 |
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