货号 | 61025 |
克隆类别 | 3PP-1H4 |
别名 | GLM1, CIMT1, NR1C3, PPARG1, PPARG2 |
同种亚型 | IgG1 |
反应种属 | Human |
来源宿主 | Mouse |
应用 | Western Blot |
使用方法 | Published Applications: WB See references for more information. Individual optimization may be required. |
供应商 | Active Motif |
纯化方式 | Protein G Chromatography |
免疫原 | This PPAR-gamma antibody was raised against a peptide within the N-terminal region of human PPAR gamma 1 and gamma 2. |
背景 | Peroxisome Proliferator-Activated Receptors (PPARs) are nuclear receptors involved in lipid transport and metabolism. As such, their roles in chronic diseases such as diabetes, obesity, atherosclerosis and cancer are heavily investigated. Transcriptional activity of PPARs is regulated by fatty acid binding. Three PPAR isotypes have been identified: α, δ and γ. PPAR-γ stimulates lipolysis of circulating triglycerides and the subsequent uptake of fatty acids into adipose cells. PPARs bind to peroxisome proliferator response elements (PPREs) as heterodimers with the retinoid X receptor (RXR). |
运输条件 | Blue Ice |
存放说明 | Antibodies in solution can be stored at -20°C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage. |
存储溶液 | Purified IgG in 70 mM Tris (pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30% glycerol and 0.035% sodium azide. Sodium azide is highly toxic. |
计算分子量 | 55 kDa |
参考文献 |
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