| 货号 | 40954 |
| 克隆类别 | 86B1153 |
| 别名 | CD286 |
| 同种亚型 | IgG1 |
| 反应种属 | Human |
| 来源宿主 | Mouse |
| 应用 | Western Blot |
| 使用方法 | Validated Applications: WB: 2 - 4 µg/ml dilution For optimal results, primary antibody incubations should be performed at room temperature. The addition of 0.1% Tween 20 to all Blotto solutions may also reduce background. Individual optimization may be required. |
| 供应商 | Active Motif |
| 纯化方式 | Affinity Purified |
| 免疫原 | This TLR6 antibody was raised against a synthetic peptide corresponding to amino acid residues 408-424 of human TLR6. |
| 背景 | TLR6–Toll-Like receptor 6 is a member of the Toll-like receptor (TLR) family that plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize specific molecular features associated with pathogens, and mediate the production of cytokines necessary for the development of effective immunity. Many of the TLRs heterodimerize with each other to modulate receptor function. TLR6 forms a heterodimer with TLR2. TLR6 is thought to specify the sensitivity of TLR2 and contribute to its signaling capabilities through heterodimerization. |
| 运输条件 | Blue Ice |
| 存放说明 | Antibodies in solution can be stored at -80°C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage. |
| 存储溶液 | PBS containing 0.02% sodium azide. Sodium azide is highly toxic. |
| 计算分子量 | 92 kDa |
| 参考文献 |
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TLR6 mAb tested by Western blot. TLR6 detection by Western blot. The analysis was performed using Daudi whole-cell extract and TLR6 mAb at a 2 µg/ml dilution. |
