货号 | 40933 |
克隆类别 | 37A565 |
别名 | M68, TR6, DCR3, M68E, DJ583P15.1.1 |
同种亚型 | IgG1 |
反应种属 | Human |
来源宿主 | Mouse |
应用 | Western Blot |
使用方法 | Validated Applications: WB: 1 - 2 µg/ml dilution For optimal results, primary antibody incubations should be performed at room temperature. The addition of 0.1% Tween 20 to all Blotto solutions may also reduce background. Individual optimization may be required. |
供应商 | Active Motif |
纯化方式 | Affinity Purified |
免疫原 | This DcR3 antibody was raised against a full-length protein corresponding to human DcR3. |
背景 | DcR3(TNFRSF6Bortumor necrosis factor receptor superfamily member 6b) is thought to play a regulatory role in suppressing FasL- and LIGHT-mediated cell death. DcR3 acts as a decoy receptor that competes with death receptors for ligand binding. Overexpression of this gene has been noted in gastrointestinal tract tumors, and it is located in a gene-rich cluster on chromosome 20, with other potentially tumor-related genes. Two transcript variants encoding the same isoform, but differing in the 5′ UTR, have been observed for this gene. |
运输条件 | Blue Ice |
存放说明 | Antibodies in solution can be stored at -80°C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage. |
存储溶液 | PBS containing 0.02% sodium azide. Sodium azide is highly toxic. |
计算分子量 | 34 kDa |
参考文献 |
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DcR3 mAb tested by Western blot. Detection of DcR3 by Western blot. The analysis was performed using 30 µg Jurkat whole-cell extract and DcR3 mAb at a 2 µg/ml dilution. |