货号 | 39787 |
克隆类别 | 4B1-F6 |
别名 | EIF2C3 |
同种亚型 | IgG2a |
反应种属 | Human |
来源宿主 | Mouse |
应用 | ChIP/Immunoprecipitation/Immunofluorescence/Immunocytochemistry |
使用方法 | Published Applications: ChIP IP ICC/IF See references for more information. Individual optimization may be required. |
供应商 | Active Motif |
纯化方式 | Protein G Chromatography |
免疫原 | This Ago3 (Argonaute 3) antibody was raised against a recombinant protein corresponding to amino acids 1-175 of human Ago3. |
背景 | Argonaute 3 (Ago3, aka EIF2C3) is a member of the Argonaute family of proteins involved in RNAi mediated gene silencing through siRNA and miRNA effectors. The Argonaute proteins are part of RISC, the RNAi Induced Silencing Complex. Ago3, however, lacks RNase activity and does not appear to cleave target mRNA molecules. Ago3 has both a PAZ and a PIWI domain, indicative of the Argonaute family of proteins. |
运输条件 | Blue Ice |
存放说明 | Some products may be shipped at room temperature. This will not affect their stability or performance. Upon receipt, unconjugated antibodies may be stored at -20°C for up to 2 years. Fluorophore- & enzyme-conjugated antibodies should be stored at 4°C. Fluorophore-conjugated antibodies should be protected from light. Keep reagents on ice when not in storage; to avoid repeated freeze/thaw cycles, we recommend aliquoting items that will be stored frozen into single-use fractions prior to freezing. |
存储溶液 | Purified IgG in 70 mM Tris (pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30% glycerol and 0.035% sodium azide. Sodium azide is highly toxic. |
计算分子量 | 110 kDa |
参考文献 |
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