货号 | 61756 |
克隆类别 | 17-3-4-1 |
同种亚型 | IgG1k |
反应种属 | Budding Yeast, Human, Other (Wide Range) |
来源宿主 | Mouse |
应用 | Immunoprecipitation/Dot Blot |
使用方法 | Published Applications: IP DB See references for more information. Individual optimization may be required. |
供应商 | Active Motif |
纯化方式 | Protein A Chromatography |
免疫原 | This antibody was raised against 6-Methyladenosine conjugated to BSA. |
背景 | N6-Methyladenosine (m6A) ) is an RNA modification on the N-6 position of adenosine. This modification has been found to be abundant in the 3’ UTR and stop codons of mammalian mRNA. m6A is associated with miRNA binding sites suggesting a potential role in epigenetic gene regulation. FTO and ALKBH are demethylases for 6-methyladenosine while a multiprotein complex that includes METTL3 functions as the methyltransferase. Recent findings revealed that m6A is also present on metazoan DNA, suggesting a genuine epigenetic role for this modification in the context of DNA as well. |
运输条件 | Blue Ice |
存放说明 | Antibodies in solution can be stored at -20°C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage. |
存储溶液 | Purified IgG in PBS with 30% glycerol and 0.035% sodium azide. Sodium azide is highly toxic. |
计算分子量 | Not Applicable |
参考文献 |
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