STAT3 antibody (pAb), sample
货号:
61646 基本售价:
1435.5 元 规格:
10 ul
产品信息
概述货号 | 61646 |
同种亚型 | IgG |
反应种属 | Human |
来源宿主 | Rabbit |
应用 | Western Blot |
性能供应商 | Active Motif |
纯化方式 | Affinity Purified |
免疫原 | This antibody was raised against a peptide within the N-terminal region of human STAT3. |
背景 | STATs (signal transducers and activators of transcription) are a family of 7 transcription factors that form part of the JAK-STAT signaling cascade. This cascade is the basis of the signal transduction mechanism for many cytokine receptors. Once activated by phosphorylation by JAKs, STATs translocate to the nucleus. Accumulation of STATs in the nucleus is both rapid and tightly controlled. A number of factors regulate the JAK-STAT pathway including STAT dephosphorylation by phosphatases, altered nuclear import-export dynamics of STAT, and STAT gene activation antagonists such as SOCS (suppressors of cytokine signaling) and PIAS (Protein Inhibitors of Activated STATs). |
运输条件 | Blue Ice |
存放说明 | Antibodies in solution can be stored at -20°C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage. |
存储溶液 | Purified IgG in PBS with 30% glycerol and 0.035% sodium azide. Sodium azide is highly toxic. |
参考文献 | |
声明本官网所有报价均为常温或者蓝冰运输价格,如有产品需要干冰运输,需另外加收干冰运输费。 |
参考图片STAT3 antibody (pAb) tested by Western blot. Detection of STAT3 by Western blot analysis. Nuclear extract of HepG2 cells (30 µg) probed with STAT3 antibody at a dilution of 1:2,000. |