货号 | 61598 |
同种亚型 | IgG |
反应种属 | Human |
来源宿主 | Rabbit |
应用 | Western Blot/Immunoprecipitation |
使用方法 | Validated Applications: IP: 10 µl per IP WB: 1:500 dilution Individual optimization may be required. |
供应商 | Active Motif |
纯化方式 | Affinity Purified |
免疫原 | This antibody was raised against a peptide within the C-terminal region of human CABIN1. |
背景 | CABIN1 (calcineurin-binding protein 1) may be required for replication-independent chromatin assembly. May serve as a negative regulator of T-cell receptor (TCR) signaling via inhibition of calcineurin. Inhibition of activated calcineurin is dependent on both PKC and calcium signals. Component of a complex that includes at least ASF1A, CABIN1, HIRA, Histone H3.3 and UBN1. |
运输条件 | Blue Ice |
存放说明 | Antibodies in solution can be stored at -20°C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage. |
存储溶液 | Purified IgG in PBS with 30% glycerol and 0.035% sodium azide. Sodium azide is highly toxic. |
计算分子量 | 280 kDa |
参考文献 |
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CABIN1 antibody (pAb) tested by Immunoprecipitation / Western blot. 10 µg of HIRA antibody (mAb), catalog no 39555, (lane 1) or 10 µl of CABIN1 antibody (pAb) (lane 2) was used to immunoprecipitate CABIN1 from 1mg of U2OS nuclear extract. 10 µg of rabbit IgG was also used as a negative control (lane 3). The immunoprecipitated protein was detected by Western blotting using CABIN1 antibody at a dilution of 1:500. |